In arid and semi-arid regions around the world, water quality is essential in agricultural systems. The present study was evaluated Tigris River for suitability irrigation in Salah Al-Din province. Water samples were collected and analyzed for various Hydro-chemical parameters like EC, TDS, pH, total hardness (TH), Ca2+, Mg2+, CO32-, HCO3-, Cl-, SO42-, Na+, and K+, with different Irrigation indices such as Sodium percentage (Na%), Sodium adsorption ratio (SAR), Residual Sodium Carbonate (RSC), Permeability Index (PI), Kelly's Ratio (KR), Potential salinity (PS) and Hardness were also calculated. The Na%, SAR, RSC, PI, KR, PS and total hardness varied from 2.26 to 10.06 (mmol. l-1)1/2, 0.01 to 6.10 0 meq. ll-, 8.83 to 77.10%, 0.19 to 1.19 meq. ll, 1.00 to 15.16 meq. ll and 49.3 to 197.1 mg. L-1, respectively. Hence, the various parameters and indices results were concluded that the Tigris River quality was suitable to be used as a water source for irrigation. A strategic plan and regular monitoring are required to limit or reduce the pollution of the river water in order to improve the water quality in its natural condition.