The present study was conducted to determine the effect of consumption of fresh red palm and cow fat blend oils on the redox status of rats. A total of 60 rats were divided into 4 groups of 15 rats each. Group A served as normal control and were fed with pelleted growers feed. Group B were fed with pelleted growers feed mixed with 2ml/kg b.wt of red palm oil. Group C were fed with pelleted growers feed mixed with 2ml/kg b.wt of cow fat oil while Group D were fed with pelleted growers feed mixed with 2ml/kg b.wt of a blend of red palm oil and cow fat oil. Animals were sacrificed after 28 days. Blood was collected for the estimation of SOD, MDA, GPX, CAT, Vit A and E by enzyme linked immunosorbent assay with kits obtained from Sunlong Diagnostic Ltd, China. Results were presented as mean + standard deviation with p<0.05 considered significant. There was a significant increase in the MDA concentration of rats treated with cow fat oil (p=0.001) compared to the rats treated with red palm oil, blend of red palm oil and cow fat oil as well as the normal rats. There was also significant increase in the concentrations of SOD (P=0.013), GPx(P=0.002), CAT(P=0.007), CAT(P=0.011), Vit A (P=0.009), Vit E (p=0.018) for the rats treated with red palm oil and those treated with a blend of red palm oil and cow fat oil compared to those treated with cow fat oil as well as the normal rats. These finding suggests that red palm oil and a blend of red palm and cow fat oil contains more antioxidant and could be more beneficial to health than the cow fat oil.