When we discuss homoeopathy, invariably the Bowel Nosodes group drugs are an integral part of homoeopathic materia medica. All these are leading anti-inflammatory & immune-boosting dealing drugs of homoeopathic materia medica, the nosodes from the bowel are the drugs that the article discusses. Nosodes are those drugs in homoeopathy which are prepared from the disease related products or organisms. This means these are the gut bacteria from which medicines are prepared as per the homoeopathic pharmacopeia. The article looks into the role of one such bowel nosode from the Oscillibacter species. The article looks into the scientific aspects of these dealing drugs to deal with hypercholesterolemia. The future use of the drugs in the Non-Communicable Disease (NCD) like high cholesterol levels on a large scale will only benefit the masses. The drugs are cost effective, therapeutically active with no side effects & these properties only augur well for large scale application of homoeopathy on NCDs. The use of these drugs is authenticated by the scientific research of the gut bacteria on reducing cholesterol. For the benefit of the masses, the homoeopathic perspective, use & a treatment protocol is described in this article. The protocol is based on the bowel nosodes that can help in reducing cholesterol. The authority books of homoeopathic materia medica & the encyclopedia of homoeopathy are referred in the article.