Background: Breast cancer is the most common cancer worldwide. Mortality have reached a plateau and appear to be dropping this decline has been attributed to several factors, such as early detection through the use of screening mammography and appropriate use of systemic adjuvant therapy. Aims: To assess the value of type breast screening in women more than 40y age group and to assess the value of BIRAD system application in breast screening. Patients and methods: The study was performed during the period covered fourteen months from October 2012 to December 2013 in the Oncology teaching hospital in Baghdad Medical Teaching Complex. The study include 350 females with an age more than 40 years, Mammograms were performed for them and categorized using the Breast Imaging-Reporting and Data System (BI-RADS). Correlations between imaging findings, risk factors and pathological findings were analyzed. Result: Present study show that there was no cancer diagnosed in women categorized as BIRAD I, II and III. However among 8 women with BIRAD IV and V 75% had malignant disease and 25% had benign lesions. Correlation was found between known risk factor (age, menopause, early menarche less than 12years and BMI) and cancer diagnosis. Conclusions: Breast screen is very effective and important in discover breast cancer in asymptomatic women by using the mammogram which is an effective tool in detecting breast cancer in breast screening. BIRAD system minimized both over-utilization and under-utilization of follow-up tests/procedures.