Enterprises in Phu Tho Province play a pivotal role in generating employment and contributing to the local budget. In recent years, although they have made notable achievements and played a significant part in the socio-economic development of the province, their operations and contributions have not yet fully realized their potential. This paper evaluates the current state of business performance of enterprises in Phu Tho Province, Vietnam, and offers a range of strategic solutions to enhance their business efficiency in the forthcoming period.