Quality of education is determined by conditions of learning in institutions. There are real concerns raised by stakeholders regarding quality of education in Early Childhood Development and Education (ECDE) centers in Emuhaya Sub-County, Kenya. Factors contributing to poor quality assurance control in implementation of ECDE curriculum are yet to be established. The purpose of the study was to establish quality assurance factors influencing implementation of ECDE Curriculum in Emuhaya Sub-County, Kenya. The study was based on descriptive survey design. It consisted of 196 teachers drawn from 98 ECDE Centres and 1Program Officer. Simple random sampling technique was used to select 65 teachers. Saturated sampling technique was used to select 1 program Officer. Data was collected by questionnaire, interview schedule and observation schedule. The study concluded that: ECDE Centres did not have adequate teaching - learning resources and facilities suitable for ECDE children. This inhibits implementation of ECDE Curriculum. The study recommends that; Intensive monitoring and evaluation system should be developed and implemented to enhance quality assurance by employing more ECDE Quality Assurance and Standards Officers to work hand in hand with The Program Officer in the process of manning ECDE subsector.