This research evaluated how chamomile extract affects male laboratory rats with type 2 diabetes through changes in immunoglobulin measurement, enzyme activity and weight management. The research took place at the College of Agriculture and Veterinary Medicine part of Tikrit University during a 28-day period. The results showed that diabetic rats treated with chamomile extract experienced improved immunity through increased IgG and IgM levels together with decreased liver enzyme levels of AST, ALT and ALP. The consumption of chamomile extract prevented diabetes-related weight reduction since it helped control body mass. The administration of chamomile extract results in these effects because of its antioxidant and anti-inflammatory nature, which enables enhanced liver function combined with metabolic control and improved immune system operation. These results indicate that chamomile extract might function as an additional therapeutic approach to manage diabetes by preventing metabolic and immune complications of the disease.