Sexually transmitted infections (STIs) remain a major public health concern, particularly in developing countries. Sexually transmitted infections (STIs) among women is on the increase. This growing trend may be linked to changing sexual behaviors, limited access to reproductive health services, and poor awareness of preventive and early treatment options. This study is aim to evaluate the Epidemiological Assessment of The Rising Incidence of Sexually Transmitted Infections among Women in Urban Communities of South-South Nigeria. This is a cross-sectional study involving 250 women who are within their reproductive age with age range 18-22, 23-27, 28-32, 38-42, 38-42, and 43-47years. A well - structured self-administered questionnaire was issued to each participant. The study lasted for 2 months (May to June ending). Statistical analysis of data was done using SPSS Version 26. P value < 0.05 was considered significant for data. The results shows that the participants were between 18 and 47 years of age, 64% had tertiary level of education, 60% were single, 64% civil servants, 60% were aware of STI, 68% had knowledge about STI, 76% enjoyed raw sex without condom, 60% are not faithful to one partner, 76% were infected with STI, 80% use herbal medication as choice of treatment, and 80% had complications such as difficulty in passing urine (20%), painful urination (24%), vaginal itching (24%), and vaginal itching (32%).