South Asian Research Journal of Pharmaceutical Sciences (SARJPS)
Volume-7 | Issue-06
Original Research Article
Pharmacognostic Evaluation and Anti-Inflammatory Potential of Flavonoid Rich Extract of Trigonella Foenum-Graecum Seed Ameliorate
Mr. Sankalp K. Jadhav, Mr. Ravi Shankar Rao, Ms. Pooja S. Pote, Mr. Mahesh S. Ghugare
Published : Dec. 29, 2025
Abstract
Trigonella foenum graecum has been traditionally claimed that seeds of Trigonella foenum graecum are useful in the management of anti-inflammatory and anti-oxidant activity. In the present study, anti-inflammatory and anti-oxidant activity of Trigonella foenum graecum hydroethanolic extract was evaluated. The physicochemical parameters were found to be within acceptable limits, while phytochemical analysis confirmed the presence of Steroids, Alkaloids, Flavonoids, Saponins and tannins. The prepared plant extract demonstrated significant antioxidant activity with an IC50 value of 18.64 μg/ml, compared to the standard IC50 of 5.40 μg/ml. Additionally, the plant extract exhibited notable anti-inflammatory activity based on percent inhibition results. These findings suggest that Trigonella foenum graecum hydroethanolic extract hold considerable promise as an effective therapeutic agent with potent antioxidant and anti-inflammatory properties. Thus, hydroethanolic extract of fenugreek seeds has significant anti‑inflammatory and anti‑oxidant activities which are due to the presence of its active chemical constitutes.