The study assessed the diversity of the indigenous tree species and also produce of a compendium of information on the various medicinal uses of the indigenous tree species and their parts in Adamawa State, Michika local government seven districts; Bazza, Futu, Garta, Madzi, Michika, Nkafa, Zah. Sample plots method was used in the assessment of the indigenous tree species using questioner. All indigenous Medicinal plants information on ethonomedicinal uses was obtained through oral interviews and the through the questioners. Age group and occupation was considered such as; Local healer, Herbalist, Traditional birth attendance, experienced parents, patients and students were randomly selected for this purpose. Result of the findings indicated that 48 common indigenous medicinal plants species were encountered in all the seven districts inventoried in the study. Results further indicate that Acacia seyal, Parka biglobosa, Adonsonia digitata ,Khaya senegalensis, Ziziphus spina-christi, Azadirachta indica, Moringa oliefera, Ficusgnaphalocarpa, Mangifera indica, Cassipourea congoensis, Psidium guajava, Vitex doniana, Nuclea latifolia, Anacardium occidental, Nuclea latifolia, Carica papaya, Annona senegalensis, Citrus aurrantium, Eucalyptus indica, Tamarindus indica, Vernonia amygdalina, Cassia occidentalis, Citrus Paradise, Momordica charantia, Anogeissuss, leiocapus, Ficus vollis, Gemlin arborea, Borassus aethiopum, Abrus precatorius, Elaeophorbia drupifera, Artemisia maciverae, Vitellaria paradoxa, Zizipus Mauritania, Daniella oliverii, Anogeissus leiocarpa, Ficus sycomorus, Balanites aegyptiaca, Conorandus panados, Deterium microcarpum, and .Balanites aegytiaca were common to all the districts. While all other species were found in either three, two or one districts. Diversity Index community response on resource and ranking of medicinal plant in the seven districts indicate Nkafa and Zah was observed to have higher ranking. It was observed that the plant parts used for medicinal purposes are roots, barks, leaves, stems, Epiphyte etc. The formulation for medication include; boiling, soaking, etc. Methods of administration include, drinking, bathing, adding to food as spices and chewing. Among the ailments treated are dysentery, diarrhea, diabetes, Tuberculosis, Meningitis, Blood tonic, High blood Pressure, Worms, Typhoid Fever, Cancer, Malnutrition, Tumors, Wound Healing, Jaundice, Epilepsy and Rheumatism. It can thus be concluded that the sharp decrease in disease outbreak in the districts and villages was as to the increasing economic and health values placed on medicinal plants, documentation on ethnobatanical knowledge is a way to understand the use of different plant species to cure various ailments, diseases and means to conserve these natural resources. From the findings of the study the following recommendations are hereby made; the local people need to be trained, encouraged and supported on how to conserve and manage the medicinal plant species, Young generation need awareness to avoid negative impacts on the medicinal plants and associated knowledge in the area, hence, documentation of the medicinal plants of the area needs to continue.