Aim: To assess feasibility, safety and long-term outcome of a water-soluble contrast agent (Gastrografin™) in surgical neonates/infants who present with ABSO. Method: 18 Neonates, who continued to exhibits signs of intestinal obstruction after one week post surgery, were given 1-2 mls/kg of oral Gastrografin for 5-8 days. Result: All but one patient could be fed within 12 hours and discharged home soon afterwards. A single patient retuned 6 months later with ABSO and was similarly treated again. There was no mobility or mortality due to this technique. Main Conclusion: Gastrografin contrast give orally can result in relief of ABSO, as similarly described in adult and older children.