Objectives: Osteoporosis is an asymptomatic disease characterized by low bone mass and loss of the quality of bone, which increases the risk of a bone fracture. This is the most common reason for a broken bone among the geriatric population. Educational intervention is ideal for osteoporosis because many of its risk factors can be treated, such as poor dietary calcium intake and limited amounts of physical activity. This study aimed to determine the effect of the prevention program on knowledge regarding osteoporosis among geriatrics and to associate the level of knowledge with selected demographic variables. Materials and Methods: Pre-experimental design adopted. Totally 60 geriatric people aged >60 years visited the selected chronic outpatient clinic were selected by using a convenient sampling technique. The data collected through a structured questionnaire to measure knowledge regarding osteoporosis. The educational awareness program was conducted as a group for 30 minutes. The pre-test and post-test scores were analyzed, in terms of both descriptive and inferential statistics. Results: Out of 60 samples 15% & 55% had adequate knowledge, 61.7% & 40% people had average knowledge and 23.3% & 5% had inadequate knowledge in pre and post-test. The paired ‘t’ test value 6.5147 is highly significant (P<0.01) which proved the effectiveness of osteoporosis prevention programme (OPP). There was a significant association found between the level of knowledge and education and BMI at P<.05 level. Conclusion: Prevention is the most effective method of decreasing the morbidity and mortality of osteoporosis. Nurses have a major impact on educating geriatrics about the risks for osteoporosis.