Nurses focus on medical diagnosis and they move away from providing the holistic care to their patients. This impairs the essence and goal of nursing science. Nursing theories have been marginalized in several parts of the world including South Asian countries like Pakistan. The fact that nursing science and biological sciences have different philosophical underpinnings is important to be realized by nurses. The authors of this article have highlighted educational, administrative and policy level issues in nursing theory guided practice and their practical solutions with future implications in Pakistan. The paper may serve as a whistle blower to inform future directions in regards to nursing theory guided practice.