COVID-19 pandemic has made it impossible for the current workforce to interact with stakeholders, and this is to mitigate the viral spread for a significant proportion of the workforce. The pandemic situation in the country led both employers and employees to look for alternative work arrangements. According to various research findings, the empirical knowledge gap was identified regarding the work from home and job satisfaction of women employees in Sri Lanka. To fill this empirical knowledge gap, this study was conducted with two research objectives to determine the level of WFH and job satisfaction and explore the impact of WFH factors on the job satisfaction of women employees who WFH in Sri Lanka. Primary data were collected from 120 women employees working from home for the companies located in the Colombo area, Sri Lanka using structured questionnaires. The data were analyzed using descriptive statistics and multiple regression analysis. Based on the findings of this study, the level of the WFH factors and job satisfaction was high. Multiple regression analysis revealed that among all WFH factors, seven of them including time planning skills, reduce the time for communication with co-workers, possibility to WFH in case of sickness, supervisor’s trust and support, possibility to save expenses, possibility to take care of family members and suitability of working place at home has a significant impact on the job satisfaction of women employees and the possibility to access the organization documents at home has no significant impact on the job satisfaction of women employees. The findings of this study identify a significant positive effect of WFH on the job satisfaction of women employees. Moreover, the results of this study guide to exercise effective strategies to direct employees for the usage of modern technology to access documents online.