Vegetables are major sources of vitamins, minerals and bioactive components such phytochemicals and antioxidant that help in reducing the risk of diseases. The aim of the study was to determine the proximate composition, phytochemical screening and mineral composition of Amaranthus spp. leaf extract. The proximate composition and phytochemical screening were determined using conventional laboratory methods while the mineral composition of the leaves was determines using atomic absorption spectrophotometer. The proximate analysis of the leaf extract showed that it contains carbohydrate (48.6%), protein (18.2%), fats (5.4%), crude fibre (10.6%), moisture content (8.3%) and ash content (13.3%). The preliminary phytochemical screening of Amaranthus spp. leaf extract revealed the presence of Alkaloid, terpenoid, flavonoids, steroid, phenol, saponins and tannin. Quantitative phytochemical analysis of the extract showed that the flavonoids is the most abundant constituent in making about 11.6%, followed by steroid, alkaloid and phenol constituting 4.3%, 3.6% and 3.1% respectively. The mineral analysis of the extract indicate the presence of calcium (68.5 mg/100g), potassium (67 mg/100g), magnesium (89.8 mg/100g), phosphorous (62.5 mg/100g), zinc (8.0 mg/100g), iron (15.8 mg/100g) and copper (6.2 mg/100g). From the findings of this study, it is concluded that Amaranthus spp. leaf has therapeutic potential and can be used dietary supplements.