Renal Tubular acidosis (RTA) is a tubular acidification disorder characterised by severe electrolyte disturbances mainly hypokalemia and normal anion gap acidosis out of proportion to GFR. Sjogrens syndrome though a rare disorder usually causes distal RTA however few studies have reported cases of Proximal RTA as well. Here we report a case of Acute onset quadriparesis in a young female which was attributed to Hypokalemia. Further evaluation revealed that RTA probably was proximal in origin due to Sjogrens Syndrome.