Hyperlipidemia is a disease portrayed by an extension, in any incident, one of the plasma lipids, including triglycerides, cholesterol, cholesterol esters just as plasma lipoproteins including outstandingly low thickness and low thickness lipoproteins close by diminished high thickness lipoproteins levels. This stature of plasma lipids is among the leading risk factors related to cardiovascular illnesses. The present review focuses on the sorts of hyperlipidemia, lipid processing, the pathophysiology of hyperlipidemia, treatment frameworks for raised lipid profiles. In the interim statins and fibrates remain the major antihyperlipidemic administrators for the treatment. The fortune spot of the plant domain has different plants to treat this ailment. The indigenous course of action of the drug gives bountiful data about plants available for the treatment of hyperlipidemia. The review also lightens the role of nutraceuticals in hyperlipidemia therapy. The search was performed in PubMed, PsycInfo, Web of Science, Scopus, and Medline databases. A quality assessment yielded a total of 60 papers to be considered for the review by using strict inclusion and exclusion criteria.