Background: Coronaviral disorder (COVID-19) is a worldwide pandemic originating in Wuhan, China and spreading rapidly across the world and infecting human beings independently of age, sex, and race. There is still a lot to learn, given the nature of this infection. People with COVID-19 have reported a variety of symptoms, ranging from minor symptoms (e.g., common cold) to serious conditions such as bronchitis, pneumonia, severe acute air distress (ARDS) syndrome, multi-organ failure and even death. Comorbidity is a key component in the pandemic result COVID-19 which frequently results in fast and serious development, including death. Objective: The research examined the socio-demographic characteristics and characteristics of COVID-19 and assessed the effect of comorbidity on their hospital result. Methods: This observatory research was placed from April 2020 to September 2020 at Rajshahi Medical College, Rajshahi and CDM Hospital, Rajshahi (COVID-19) specialized hospital for a period of 06 months. All clinically suspected RT-PCR confirmation patients were included. Data were gathered via thorough patient history and then reviewed, consistency checked, and resulted modified. The coded data were examined using the SPSS software program after editing and coding. Results: The research included 627 patients, 552 of whom were in the covid ward and 75 in the ICU. 354 of Covid's (552) hospitalized patients were male (64.13%) and 198 (35.86%) were female (1:0.56%) patients. Young patients (age 19-50) were more impacted and hospitalized (62.86%), urban patients (52.61%) more susceptible than rural patients (47.28 percent). The primary symptoms were fever, cough and shortness of breath (63.04 percent, 45.47, and 42.39 percent, respectively). 44.20 per cent of patients with 55.79 per cent co-morbidities are not comorbid. Concerning co-morbidities. The major concurrent illnesses were hypertension (17.57%), followed by diabetes (15.94%), ischemic cardiac disease (05.60%), chronic blockage (05.60%), chronic renal disease (2.2%), heart attack (1.44%) and cancer (1.54 percent). (0.36%) of the population. A total of 75 patients, most of them seniors, required ICU treatment (64 out of 75). With regards to hospital outcomes, 96.74% (534 of the 552) and 45.34% (34 of the 75) of ICU admitted patients were released safely, whereas 03.2% and 54.66% of ICU patients hospitalized had expired. The number of fatalities among seniors was greater (n=43; 72.88 percent). Hypertension, diabetes and ischemic heart disease were often associated with dementia (42.37 percent, 37.28 percent, and 16.94 percent, respectively). Conclusion: The huge number of people with fever, poisoning and shortness of breath. The percentage of COVID-19 hospitalizations linked to mortality has remained high the elderly and those suffering from one or more comorbid illnesses. Elderly and comorbid patients should thus take all the required measures to prevent SARS CoV-2 infections.