Incidence of premature aging, heart diseases and many other such disorders are on a rise and a matter of great concern worldwide. The environmental factors, consuming tobacco and smoking are the main causative factors of oral cancer. The effects of these can be reversed to a limit by consumption of antioxidants. This article gives detailed description about antioxidants, its mechanism of action and its role in different disorders. This will help educate the readers about the beneficial properties of antioxidants and how it may benefit the healthy and diseased individuals.