Abstract: This study was designed to study of liver diseases using triple-phase computed tomographic scan protocol in Sudanese patient whom presented to computed tomography scan department at Kuwaiti specialized hospital-Sudan, when the liver is investigated using computed tomography machine (CT). Methodology: 16 slice GE-Optima (2016) CT scanner was used to scan the 51 patient with liver disease, in period from April to August 2018 where the time and pattern of enhancement were assessed using stander triple phase protocols where the true angiographic phase was done using SMART prep option . The data was initially summarization into mean, stander deviation and percentage in a form comparison tables and figures. Results: Out of 51 examined samples (mean age of 54 years male and female ratio (30) (86.8%), (21) (41.2%) were (16) (21.3%) of patients have hepatocellular carcinoma to liver between disease. the accurate time of three phases in exposure time was (8.13-19.6-8.2s) and delay time was (5.16-22.11-359s). The Computed tomography enable detecting and characterization of liver diseases using the proper timing contrast and protocols.