Abstract: The immune system is highly dependent on precise communication between cells for optimal function, and any damage to the signaling systems involved will result in an impaired ability to mount an immune response. A cross-sectional survey of 212 participants from different cities of Iraq was conducted to explore the effect of eating fruits & vegetables and taking vitamins on the immunity status like recurrent infection, COVID19 and chronic diseases. The data collected by using survey targeted to all cities of Baghdad. The questionnaires were distributed online using Google Forms. It will be a convenient sample. The collected data was analyzed by using statistical package social science (SPSS) program version 23.0 and demonstrated in tables and graphs. Sample test was used to decide if there is statistical difference or not. The survey generated 212 responses. Regarding on the question about the chronic disease 94.3% of the answers don’t have chronic diseases and 5.7% were had chronic diseases. Concerning the question about COVID19 infection65.1% of the answers was not infected and 34.9% were infected. The question regarding the recurrent infection 18.4%suffered from recurrent infection and 81.6% were not. The question regarding eating fruits & vegetables89.2% eating frequently and 10.8% were not. The question regarding taking vitamins50.0% of participants were taking vitamins and 50.0% were not. The increase immune protection by immunostimulant factor from food like eating fruits & vegetables or by therapeutic adjuvant like vitamins and minerals is useful in increase immunological status and help in protection against microbial infection.