Objective: To evaluate racial and sex-based differences in route of medication administration for emergency department migraine treatment, using parenteral versus oral medication administration as a proxy for more rapid acute treatment. Background: Each year, migraine affects over 1 billion people and are the second leading cause of disability worldwide. Of those affected, migraine are present in women nearly 3 times more than men, leading to the stigma of migraine being “a woman’s complaint”. This sexual disparity is compounded by racial inequality. Studies have found that African American patients are often undertreated for pain. However, there is a gap in the literature about how this disparity translates to migraine treatment, specifically considering patient sex. Methods: This was a retrospective database analysis, extracted from the Cerner Health Facts database (Cerner Corporation, Kansas City, MO), consisting of patients aged 12-25 who presented to the emergency department for migraine treatment within the years 2015 and 2016. Among the dataset of 1000 randomly de-identified patients, 729 patients presented to the emergency department only once within the time frame. Additionally, we conducted a statistical analysis to determine the significance of the association between more rapid acute treatment with race and sex. Results: African American patients were 37% less likely to receive parenterally administered medication compared to Caucasian patients (Odds ratio, 0.63; 95% confidence interval, 0.45-0.88; P=0.01). Furthermore, female African American patients were 46% less likely to receive parenterally administered medication compared to their female Caucasian counterparts (Odds ratio, 0.54; 95% confidence interval, 0.37-0.78; P=0.001). Our results indicated no statistically significant difference in route-based treatment differences between African American males and Caucasian males. Conclusions: Significant racial disparities exist in the administration of parenteral migraine medication, with African American patients, particularly female African American patients, being less likely to receive parenteral treatment compared with their Caucasian counterparts. By establishing where racial disparities exist in the health setting, we can work towards closing the gap and moving towards equity. Plain Language Summary: Migraine is a common and disabling condition, but little is known about whether race and sex influence how rapidly patients receive treatment in the emergency department. In this retrospective study of patients aged 12–25 years with migraine-related emergency department visits, African American patients, especially African American female patients, were less likely than Caucasian patients to receive parenteral administered medication. These findings suggest that racial and sex disparities may affect acute migraine treatment and highlight the need for more equitable emergency department pain-management practices.

Introduction: Artificial intelligence (AI) has been increasingly revolutionizing the field of neurology, yet formal training in AI tools, appraisal, and limitations remains limited in residency education. Neurology training should reflect growing advancements in technology, as this gap risks inappropriate reliance or underutilization of AI tools. Objectives: To evaluate how a structured, three-session artificial intelligence curriculum for neurology residents improves AI literacy, clinical confidence, and critical appraisal to use AI tools in neurologic practice. Methods: We conducted a prospective quality improvement study involving 9 neurology residents at University Health through an AI curriculum consisting of 3 sessions that incorporated case-based learning, ethics discussions, and exposure to real-world AI tools (Appendix A). Using the Kirkpatrick model, we aimed to measure outcomes at 3 levels: reaction, learning, and behavior. To do this, we administered a pre- and post-survey (Appendix B) using 5-point Likert-scale items and open-ended questions. These were analyzed with the Wilcoxon signed-rank test for paired ordinal responses and qualitative analysis. The main themes assessed included confidence and knowledge, adoption and attitude, and risk awareness. Qualitative measures included perceived effectiveness of the lecture series and self-reported, intended behavior change. Results: Residents demonstrated improvements in confidence and knowledge, as well as in attitudes and adoption. The highest level of improvement was observed in confidence and knowledge, with a 0.96-point change (p value = 0.004). In terms of resident attitudes, 89% agreed that the lecture series improved their understanding of AI in neurology, the content was relevant to their practice, and that they are more prepared to engage with AI. Intended adoption and attitudes showed a favorable but non-significant trend, with a 0.17-point improvement (p=0.078). Finally, risk awareness had a non-significant, minimal improvement from 0.06 points. Conclusion/Discussion: Implementation of a structured, discussion-based AI curriculum significantly improved neurology residents’ confidence, knowledge, and skills in AI tools. This project demonstrates that targeted educational interventions can address critical gaps in AI literacy.

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Women who are yet to marry are not happy and are faced by several degrees of psychological trauma such as isolation, low self-esteem, depression, anxiety, shame, loneliness and family pressure. Psychological factors affecting reproductive-aged women who are yet to marry are shaped by a mix of individual emotions, societal expectations, cultural norms, and life experiences. One of the most dominant psychological factors is marriage pressure. This study aimed to Assess Psychological Factors Affecting Reproductive-Aged Women Who Are Yet to Marry In South-South Nigeria. This was a cross-sectional study involving 250 women. Participants’ age is between 18 to 40 years and above. A well-structured questionnaire was administered to participants. The study lasted for a period of 3 months. Statistical analysis was done using SPSS version 25.0 and p < 0.05 was significant. The study revealed that 60% of the participants were between 35 and 39 years old, 68% had tertiary education, 60% residence in the city, 60% not in a relationship, 80% are under family pressure to get married, 80% are not comfortable, 76% feel pressured to marry after her friend’s marriage, 80% are anxious of not being married, 76% said remaining unmarried affects my self-esteem, 76% feel emotionally unstable, 80% feel lonely, 76% are not happy been single, 80% agreed that fear of divorce or marital problem affects my decision to marry, 76% had depression, 68% faced isolation, 80% are ashamed of themselves. The study shows that majority of the participants are facing different degrees of psychological trauma.

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Anxiety disorders are among the most prevalent mental health conditions worldwide and are commonly understood within biomedical frameworks as arising from complex interactions of genetic, neurobiological, psychosocial and environmental factors. Although existing treatments, including pharmacotherapy and psychotherapy, can alleviate symptoms, they often fail to provide definitive or preventive solutions for all patients. The persistence of unexplained symptoms and treatment-resistant cases suggests that additional underlying mechanisms may exist beyond current scientific models. Therefore, this study explores a Dharma-based perspective, as articulated in the Guan Yin Citta Dharma Door, which attributes anxiety disorders to karmic and spiritual causes. Through analysis of practitioner-reported cases and question-and-answer records, this study examines the potential therapeutic effects of practices such as vow-making, Buddhist Scripture recitation, and life release. The findings indicate a consistent pattern of perceived symptom alleviation and recovery following sustained engagement in these practices. These results suggest that Dharma-based interventions may offer a complementary, holistic approach to understanding and managing anxiety disorders, warranting further systematic investigation.